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STAFF HIGHLIGHT Jeff White MD

2020 3 24 two program announcements that resulted from the 2017 microbial based cancer therapy meeting R21 and R01 We ve also collaborated with the Natural Products Branch NPB in DCTD s Developmental Therapeutics Program to facilitate products being brought to NCI for anti cancer screening For example we helped

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AI and Drug Discovery Attacking the Right Problems

I ve been meaning to write some more about artificial intelligence machine learning and drug discovery and this paper open access by Andreas Bender is an excellent starting point I m going to be talking in fairly general terms here but for practitioners in the field I can recommend this review of the 2020 literature by Pat Walters which will take you through a number of

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Djaja Djendoel Soejarto Ph.D

2017 1 31 NCI Sponsored Plant Explorations Southeast Asia For the past 16 years I have had the privilege of running a plant exploration program under the sponsorship of the National Cancer Institute NCI The focus of the program is the tropical rain forests of Southeast Asia from Bangladesh east to Papua New Guinea.

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Screening of Plants Used as Traditional Anticancer

2020 10 16 Screening of Plants Used as Traditional Anticancer Remedies in Mkuranga and Same Districts Tanzania Using Brine Shrimp Toxicity BioassayAuthors Daniel Z Matata OlipaNgassapa Francis Machumi and Mainen J Moshi.Presenter Dr Pax J MasimbaContact Institute of Traditional Medicine Muhumbili University of Health and Allied Sciences Dar es

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Getting to Know 11 Stadtmans

2021 9 23 Each year NIH aims to hire upward of 10 researchers through this prestigious program Six of the new Stadtmans work in the National Cancer Institute s NCI s Center for Cancer Research Efsun Arda Steven Cappell Anupama Khare Natalie Porat Shliom Sergio Ruiz Macias and Joana Vidigal Two work in NCI s Division of Cancer

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Glance at a

2020 6 24 program staff interns and directors alike Although they were not the primary target audience members of the public health research community also utilized Theory at a Glance both as a quick desk reference and as a primer for their students The National Cancer Institute is pleased to sponsor the publication of this guide but its

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Cancer Prevention and Control CIRB

From 2002 2006 she was a Post Doctoral Fellow in the Ethics of Prevention and Public Health track of the Cancer Prevention Fellowship Program at the National Cancer Institute NCI For more than 15 years Dr Wasson has worked with and taught a range of health professionals and students as an educator researcher and clinical ethicist.

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Nci training test 44 New Courses

NCI Plus Training Scales Training 919 909 3688 4 hours ago NCI Instructor Training Preparation This training is for candidates that would like to become an NCI Plus Instructor for your Agency or to have the ability to train agencies in the states that NCI is an approved curriculum It is recommended that you are NCI Participant trained I am a Co Teacher for the NCI

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HSI HEALTH SCIENCES INSTITUTE

2012 12 17 by the National Cancer Institute NCI In 1976 the NCI included Graviola in a plant screening program that showed its leaves and stems were effective in attacking and destroying malignant cells But the results were part of an internal NCI report and were for some reason never released to the public.1 Since 1976 there have been several

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TEAM Webinar Series

2020 7 24 View archived webinars from the Transforming Epidemiology through Advanced Methods TEAM Webinar Series hosted by NCI s Epidemiology and Genomics Research Program Topics include participant engagement data coordination mHealth tools sample selection and instruments for diet physical activity assessment.

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Copy of CCI00166

2012 5 23 dom screening program conducted by the National Cancer Institute NCI which has maintained a plant screening program with varying degrees of ener gy since 1960 Today the NCI employs several plant gathering strategies It also examines specimens not only for their anticancer effects but also for their abil

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US National Cancer Institute–China Collaborative Studies

2017 11 13 The National Cancer Institute NCI is interested in exploring different types of complementary and alternative medicine CAM interventions with regard to cancer prevention treatment and symptom management Two CM anticancer herbal medicines clinically used in China were studied in the NCI intramural research program by Drs Joost

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Plants as a Source of Anti Cancer Agents

2020 8 22 spanned a period of some 30 years from the early 1960s to the 1990s This plant collection program was terminated in 1982 but with the development of new screening technologies the NCI revived the collections of plants and other organisms in 1986 This time the focus was on the tropical and sub tropical regions of the world but it is

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About Us

2021 3 26 Dr White joined the Metabolism Branch of the National Cancer Institute NCI in 1990 as a Medical Staff Fellow where he performed laboratory research in immunology and molecular biology While in the Metabolism Branch he served in various positions culminating as director of the Clinical Trials and Clinical Care Program.

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Medicinal Plants HFS

Medicinal Plant mascot 1955 National Cancer Institute public screening center looking for cancer fighting compounds Plant Screening Program by Jonathan Hartwell In 1960 NCI commissioned botanists to bring plants to check for anti cancer compounds Just a totally random shot in the dark Arthur S Barclay brought Pacific Yew bark and scientists

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Development of a High throughput NanoBRET Screening

2021 9 1 Taking advantage of the NCI s diverse repertoire of screening libraries including those containing small molecule inhibitors known drug therapies and purified natural products a total of 74 735 pure compounds and 207 209 partially purified natural product extracts were evaluated for their effects on KRAS Q61R /CRAF WT binding Through these

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TEAM Webinar Series

2020 7 24 View archived webinars from the Transforming Epidemiology through Advanced Methods TEAM Webinar Series hosted by NCI s Epidemiology and Genomics Research Program Topics include participant engagement data coordination mHealth tools sample selection and instruments for diet physical activity assessment.

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Development of a High throughput NanoBRET Screening

2021 9 1 Taking advantage of the NCI s diverse repertoire of screening libraries including those containing small molecule inhibitors known drug therapies and purified natural products a total of 74 735 pure compounds and 207 209 partially purified natural product extracts were evaluated for their effects on KRAS Q61R /CRAF WT binding Through these

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High performance thin layer chromatography based

2021 1 30 This is in line with the widely use cut off concentration set by the United States National Cancer Institute plant screening program whereby a plant extract is generally considered to possess cytotoxic properties if its IC 50 which follows the incubation between 48–72 h is < 20 μg/mL The relative potency of the extracts can be ranked

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A Historical Overview of Natural Products in Drug Discovery

2012 4 16 In 1962 the United States Department of Agriculture USDA first collected the bark as part of their exploratory plant screening program at the National Cancer Institute NCI Figure 6 The bark from about three mature 100 year old trees is required to provide 1 gram of 19 given that a course of treatment may need 2 grams of the drug.

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Sci Hub

The Sci Hub project supports Open Access movement in science Research should be published in open access i.e be free to read The Open Access is a new and advanced form of scientific communication which is going to replace outdated subscription models.

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Plants as a Source of Anti Cancer Agents

2020 8 22 spanned a period of some 30 years from the early 1960s to the 1990s This plant collection program was terminated in 1982 but with the development of new screening technologies the NCI revived the collections of plants and other organisms in 1986 This time the focus was on the tropical and sub tropical regions of the world but it is

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Home

2021 8 16 The National Toxicology Program provides the scientific basis for programs activities and policies that promote health or lead to the prevention of disease Founded in 1978 NTP plays a critical role in generating interpreting and sharing toxicological information about potentially hazardous substances in our environment.

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Screening Plant

According to at least two reports 60 61 the U.S National Cancer Institute found that graviola stems and leaves showed anticancer activity in a plant screening program even though the results were never released to the public and are cited as unpublished data written by an anonymous author 58 These report said that not only the stem and

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NCI at Frederick Chemistry

2021 8 24 A AntiBase 2017 the Natural Compound Identifieris available to NCI at Frederick researchers as a networked CD ROM via the Scientific Library AntiBase is a comprehensive database of more than 44 000 natural compounds from micro organisms and higher fungi.

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Rhone AKEE

A read is counted each time someone views a publication summary such as the title abstract and list of authors clicks on a figure or views or downloads the full text.

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JULY

2008 5 12 Ta x ol had its origins in 1962 as part of the plant procurement and screening program jointly run by the National Cancer Insti tute NCI and U.S Department of Agriculture Plant parts were collected from the Pacific yew tree in Gifford Pinchot National Forest in Washington State Two years later researchers Mansukh

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Diet History Questionnaire III DHQ III

2020 10 22 The Diet History Questionnaire DHQ is a freely available food frequency questionnaire FFQ for use with adults 19 or more years of age The most recent version DHQ III can be used by researchers clinicians or educators to

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AI and Drug Discovery Attacking the Right Problems

I ve been meaning to write some more about artificial intelligence machine learning and drug discovery and this paper open access by Andreas Bender is an excellent starting point I m going to be talking in fairly general terms here but for practitioners in the field I can recommend this review of the 2020 literature by Pat Walters which will take you through a number of

Click to chat

Cancer Plants

In a 1976 plant screening program by the National Cancer Institute graviola leaves and stem showed active cytotoxicity against cancer cells and researchers have been following up on these findings since Much of the cancer research on graviola focuses on a novel set of phytochemicals called annonaceous acetogenins.

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Indigenous traditional knowledge protection prospects

2013 5 9 NCI was generally led by the knowledge of the Digo communities indigenous to the Simba Hills area who have used the plant to treat cancerous conditions for many years More than 27.2 tons of the shrubs were collected by the NCI from a game reserve in the Simba Hills for testing under a major screening program.

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Cancer Prevention Science

2021 10 13 NCI Cancer Prevention Fellowship Seeks Passionate Applicants to Drive the Field Forward May 25 2021 By Susan Jenks Preventing cancer today and in the future lies at the heart of the National Cancer Institute s competitive postdoctoral fellowship program which is accepting candidate applications for the 2022 class until August 16 2021.

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Fred Hutch receives 5 years of NCI funding to grow and

2019 11 22 Fred Hutch recently received NCI funding to grow and maintain a key prostate cancer cohort or large patient registry involving more than 2 100 men with early stage prostate cancer Researchers use the data to better distinguish between low risk and aggressive prostate cancers develop biomarkers that can help with early detection reduce overtreatment and more.

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Cancer Prevention and Control CIRB

From 2002 2006 she was a Post Doctoral Fellow in the Ethics of Prevention and Public Health track of the Cancer Prevention Fellowship Program at the National Cancer Institute NCI For more than 15 years Dr Wasson has worked with and taught a range of health professionals and students as an educator researcher and clinical ethicist.

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Natural Product Libraries

2021 10 12 natural product libraries 949 419 0288 sales chromadex Wide selection of high quality reference standards suited for the natural products industry focusing on dietary supplements food and beverage skin care and pharmaceutical markets.

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Good News NCI awards Dr

2017 10 19 NCI awards Dr Ruth Etzioni 5 year grant to fill gaps in cancer recurrence data Dr Ruth Etzioni a biostatistician in Fred Hutchinson Cancer Research Center s Public Health Sciences Division has received a five year National Institutes of Health grant to advance the science of cancer surveillance by developing validating and deploying a scalable automated

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